Product name: Sibutramine HCl
CAS: 106650-56-0
Appearance: White crystalline powder, Easy to be dissolved in methanol.
Melting point:193.0~195.0

Sibutramine is a medication that assists with weight-loss by altering neurotransmitters within the brain. Released neurotransmitters may attach to other nerves or they may be taken up again by the nerves that release them, a process termed reuptake. Sibutramine blocks the reuptake of the neurotransmitters dopamine, norepinephrine, and serotonin. Blocking the reuptake of neurotransmitters alters the balance of neurotransmitters within the nerve cells and thereby affect nerve function and interaction.

Patients taking sibutramine may achieve a 5-10% reduction from their baseline weight. Additionally, sibutramine-assisted weight loss has been accompanied by improvement in blood lipids (cholesterol). Sibutramine was approved by the FDA in 1997.

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